City Chemical LLC manufactures DL-iso-Citric Acid Trisodium Salt (CAS 1637-73-6), the trisodium salt of isocitric acid, supplied as a white crystalline powder that dissolves readily in water to a clear colorless solution. Each lot is released against an enzymatic assay with identity confirmed by both IR and NMR — the analytical package a research buyer needs in order to trust a substrate before it goes into an assay. Typical assay is 94.7% against a 93% minimum specification.
City Chemical LLC is a privately-held, woman-owned chemical manufacturer headquartered in West Haven, Connecticut. Backed by more than a century of combined operating history, we specialize in rare, unusual, and hard-to-find chemicals that are difficult to source elsewhere. Every order is backed by our ResponseAbilityTM commitment — a dedication to speed, accuracy, and responsiveness at every stage of the chemical purchasing process. Whether you need a small lab-scale quantity or a large industrial order, our team works to deliver the exact specification, packaging, and turnaround your project requires.
DL-iso-Citric Acid Trisodium Salt: Chemical Properties and Specifications
| Property / Specification | Detail |
|---|---|
| Appearance | Bright yellow/orange |
| Form | Powder |
| Purity | 99+% |
| Nitrate (NO3) | <0.005% |
| Chloride (Cl) | <0.001% |
| Moisture | None detected |
| Melting Point | 402°C (756°F) |
| Molecular Formula | PbI2 |
| Formula Weight | 461.05 g/mol |
| CAS Number | 10101-63-0 |
| Transport (DOT/IMDG/IATA) | UN 2291, Class 6.1, Packing Group III (Lead compounds, soluble, n.o.s.). Reportable quantity 10 lbs. Marine pollutant. |
| Product / Item Numbers | L6772-BULK (bulk), L6772-1KG (1 kilogram), L6772-250GM (250 gram), L6772-50GM (50 gram) |
Source: City Chemical LLC Certificate of Analysis, Lot 62J8 (September 3, 2026); Safety Data Sheet, SKU C1476 (revised 01/2026).
Common Uses & Applications: laboratory reagent and substrate for enzyme assays involving the citric acid cycle, including isocitrate dehydrogenase and aconitase work; metabolic and TCA cycle research; and analytical reference material for isocitrate determination.
Understanding the 93% Specification
A 93% assay on a biochemical reagent can look like 7% unidentified impurity. It is not. Typical moisture content for this material is 6.82%, which accounts for essentially all of the balance — the compound is a hydrated crystalline salt, and water is part of what you receive. On a dry basis the material is substantially pure, and identity is confirmed independently by IR and NMR rather than inferred from the assay figure alone.
This matters for anyone working quantitatively. If you are preparing a standard or a substrate solution, the moisture figure on your lot COA is the number you correct against, which is why we supply it with every lot.
DL-iso-Citric Acid Trisodium Salt for Specialized Industries
Isocitric acid is a structural isomer of citric acid and an essential intermediate in the citric acid cycle, the central metabolic pathway operating in nearly every aerobic cell. The trisodium salt is the practical laboratory form: it is stable as a solid, it weighs out cleanly, and it dissolves in aqueous buffer without the pH swing free acid would cause. That makes it the standard way to deliver isocitrate into an enzyme assay or a metabolic study.
As a manufacturer of DL-iso-Citric Acid Trisodium Salt, City Chemical LLC supplies biochemists, assay developers, and analytical laboratories who need a documented substrate rather than a nominal one. Our position as a specialty supplier means research groups can source an uncommon biochemical directly, with the same analytical documentation on a small research quantity as on a larger order.
Why Choose City Chemical?
Benefits of Choosing City Chemical Over Other Chemical Manufacturers
- DL-iso-Citric Acid Trisodium Salt, 93+% purity, available for qualified chemical buyers
- Enzymatic assay with IR and NMR identity confirmation on every lot
- Lot-specific Certificate of Analysis, including moisture content for quantitative work
- Flexible packaging options, from small quantities to larger requirements
- U.S.-based sourcing and support from West Haven, Connecticut
- Experience serving research, industrial, aerospace, military, and semiconductor markets
- Responsive customer service from a knowledgeable chemical supply team
- A broad catalog of rare, unusual, and hard-to-find chemicals
Responsive Chemical Sourcing and Custom Packaging
At City Chemical, ResponseAbilityTM is our commitment to giving every customer a faster, more reliable chemical purchasing experience — from first inquiry through final delivery. For a hygroscopic biochemical reagent, that means sealed packaging sized to how the material will actually be used, so a research group is not opening and reclosing a large container across months of work.
We offer custom, UN-certified packaging tailored to your process, from small research quantities through larger volumes for ongoing assay programs.
Quality Backed by More Than a Century of Experience
City Chemical’s reputation is built on more than a century of combined experience supplying rare and high-purity chemicals to demanding industries. As a U.S.-based manufacturer, we support reshoring and supply-chain resilience, helping customers reduce risk and transit time while maintaining the strict quality standards our customers expect on every order.
Whether you are running isocitrate dehydrogenase assays, studying central carbon metabolism, or validating an analytical method, City Chemical is ready to be your trusted source for DL-iso-Citric Acid Trisodium Salt.
Order DL-iso-Citric Acid Trisodium Salt
Ready to source DL-iso-Citric Acid Trisodium Salt for your next project? Contact City Chemical LLC today to request a quote, discuss packaging options, or ask a technical question. Our knowledgeable team is standing by to help you get the exact specification you need, delivered on your timeline.